Can HBOT help you live "forever"?

SoCal Hyperbaric Oxygen
4 days ago
2 min read

🧪 What Bryan Johnson Did

Conducted a 60‑session HBOT protocol over 90 days in a hard‑shell ZEUGMA chamber at 2.0 ATA, based on clinical protocols like those by Dr. Shai Efrati blueprint.bryanjohnson.com +1economictimes.indiatimes.com +1blueprint.bryanjohnson.com +5hpotech.com +5hpotech.com +5.
Monitored a suite of biomarkers: epigenetic age (DunedinPACE), telomere length, inflammation, cognitive performance, VO₂ max, gut health, and neuroimaging economictimes.indiatimes.com +10hpotech.com +10hpotech.com +10.

📉 Key Results Reported

Epigenetic aging markers improved: shifts in DNA methylation patterns suggesting slower biological aging aviv-clinics.com.
Telomere length increased and senescent cell counts decreased—echoing peer‑reviewed studies that showed 20 % telomere growth and 10–37 % drop in senescent immune cells cellregen.org +15hpotech.com +15aging-us.com +15.
Brain health markers: Johnson saw a 28 % reduction in his blood p‑Tau217 level—a dementia risk biomarker economictimes.indiatimes.com +5blueprint.bryanjohnson.com +5cellregen.org +5.
Cognitive clarity: He reported enhanced mental performance and recovery fortune.com +7cellregen.org +7aha-hyperbarics.com +7.

🔬 What Science Says About HBOT for Aging

Laboratory and clinical studies indicate HBOT can:
- Lengthen telomeres and clear senescent cells allure.com +15frontiersin.org +15hpotech.com +15.
- Lower inflammation and oxidative stress nypost.com +3hpotech.com +3oxyrenew.la +3.
- Stimulate angiogenesis, collagen synthesis, and tissue regeneration en.wikipedia.org.
- Boost physical performance in older adults—enhancing VO₂ max and cardiac perfusion bmcgeriatr.biomedcentral.com.
- Improve cognitive function and neuroplasticity, even post‑stroke or in healthy aging en.wikipedia.org.

⚠️ Risks & Limitations

Potential side effects: ear/lung barotrauma, oxygen toxicity, temporary vision changes, cataracts en.wikipedia.org.
HBOT isn’t a miracle cure: long-term effects still ambiguous, results from N=1 experiments like Johnson’s require broader clinical trials aviv-clinics.com +7hpotech.com +7timesofindia.indiatimes.com +7.
Experts urge foundational health practices—nutrition, sleep, exercise, purpose—before resorting to expensive therapies businessinsider.com.

✅ So—Does HBOT Slow Aging and Improve Health?

HBOT shows promising multi‑modal effects on biological aging markers, cognitive and physical performance. Bryan Johnson’s experiment, backed by a growing body of peer-reviewed studies, suggests measurable health benefits. Yet it's still emerging science: broader, randomized clinical trials are needed to confirm its safety and efficacy as a general anti-aging tool.

If you’re considering HBOT: